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This study is to prove the correlation between telomere length and Alzheimer's disease risk factors in the e lderly with mild cognitive impairment. The subjects o f this s tudy were 4 0 elderly people aged 70 years or older who were diagnosed with mild cognitive impairment using a public health center in Sejong City. Subjects were selected as non-smokers without diabetes or cardiovascular disease. As a result of correlation analysis for each urine, there was a correlation between telomere length and IGF-1. In addition, there was a correlation between β-amyloid, one of the biggest causes of Alzheimer's disease. In conclusion, it is considered to be able to present a method for preventing and treating Alzheimer's disease, depending on the telomere length. However, since the variability of telomere length is very high, there is a limit to the general biomarker. Therefore, we think that we need to demonstrate greater reliability through large-scale research and tracking studies in the future.