초록 열기/닫기 버튼


Background : Reactive oxygen species (ROS) take center stage as executers in ventilator-induced lung injury (VILI). The protein with DNA-damage scanning activity, poly (ADP-ribose) polymerase-1 (PARP1), signals DNA rupture and participates in base-excision repair. Paradoxically,overactivation of PARP1 in response to massive genotoxic injury such as ROS can induce cell death through beta


키워드열기/닫기 버튼

Ventilator-induced lung injury, Acute lung injury, Poly (ADP-ribose) polymerase-1, Poly (ADP-ribose) polymerase-1 inhibitor