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Browsing by Author "Kwangmeyung Kim"

Browsing by Author "Kwangmeyung Kim"

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  • Accurately Controlled Tumor Temperature with Silica-Coated Gold Nanorods for Optimal Immune Checkpoint Blockade Therapy 
    Wan Su Yun; Wonseok Yang; Man Kyu Shim; Sukyung Song; Ji-Woong Choi; Jeongrae Kim; Jinseong Kim; Yujeong Moon; Seonghoon Jo; Dong-Kwon Lim; Kwangmeyung Kim (The Korean Society For Biomaterials, 2024-03)
    Photothermal therapy (PTT) at mild temperatures ranging from 44 to 45 °C holds tremendous promise as a strategy for inducing potent immunogenic cell death (ICD) within tumor tissues, which can reverse the immunosuppressive ...
  • Activatable NIRF/MRI dual imaging probe using bio-inspired coating of glycol chitosan on superparamagnetic iron oxide nanoparticles 
    In Jae Chung; Seong Ik Jeon; Cha Uijun; BYUN， YOUNGRO; ICK CHAN KWON; Youngil Kim; Kwangmeyung Kim; Cheol-Hee Ahn (The Korean Society Of Industrial And Engineering Chemistry, 2019-08)
    MRI and NIRF multimodal imaging probe was fabricated and investigated. Glycol chitosan coated SPIONwas decorated by MMP-2 substrate conjugating BHQ-3 and Cy5.5 dye at each end (BCMG-SPION). NIRFsignals were recovered in ...
  • Assessment of Collagen-Induced Arthritis Using Cyanine 5.5 Conjugated with Hydrophobically Modified Glycol Chitosan Nanoparticles: Correlation with 18F-Fluorodeoxyglucose Positron Emission Tomography Data 
    차지현; 이상훈; Lee Sheen Woo; 박경순; Dae Hyuk Moon; Kwangmeyung Kim; Sandip Biswal (The Korean Society of Radiology, 2012-08)
    Objective: To evaluate the potential and correlation between near-infrared fluorescence (NIRF) imaging using cyanine 5.5 conjugated with hydrophobically modified glycol chitosan nanoparticles (HGC-Cy5.5) and 18F-fluorode ...
  • Development of a pH Sensitive Nanocarrier Using Calcium Phosphate Coated Gold Nanoparticles as a Platform for a Potential Theranostic Material 
    Cha Uijun; Cheol-Hee Ahn; Sun, In-Cheol; Lee Sang Cheon; ICK CHAN KWON; Kwangmeyung Kim (The Polymer Society Of Korea, 2012-03)
    Methoxy-poly(ethylene glycol) (mPEG)-Asp-Cys was synthesized by ring opening polymerization, and its characterization by 1H nuclear magnetic resonance (NMR) showed that the copolymer has 18 aspartic acid units and 0.95 ...
  • Hyaluronidase-Sensitive SPIONs for MR/Optical Dual Imaging Nanoprobes 
    Lee Dong-Eun; Kwangmeyung Kim; Gurusamy Saravanakumar; 구희범; ICK CHAN KWON; Kuiwon Choi; 박재형 (The Polymer Society Of Korea, 2011-08)
    This study developed new enzyme-specific superparamagnetic iron oxide nanoparticles (SPIONs) with potential as a multimodal probe in magnetic resonance (MR) imaging and optical imaging. For the MR/optical dual imaging, ...
  • Imaging of tumor-associated macrophages using near-infrared fluorophore-conjugated dextran-sulfate nanoparticles 
    Seung Taek Hong; Dong Gil You; Mihee Jo; Chan Ho Kim; Youngjin Choi; Chansoo Kim; Jae Hyung Park; Kwangmeyung Kim; Ick Chan Kwon; Ju Hee Ryu (The Polymer Society Of Korea, 2023-12)
    Tumor-associated macrophage (TAM) imaging is critical to provide greater insight into cancer diagnosis and treatment, but current strategies to accomplish this are often inadequate. In this study, we prepared a TAM imaging ...
  • Lipid-Based Emulsion System as Non-Viral Gene Carriers 
    Heayun Nam; ICK CHAN KWON; JEONG SEO YOUNG; PARK， JAE HYUNG; Kwangmeyung Kim (The Pharmaceutical Society Of Korea, 2009-05)
    The genetic materials for systemic administration meet a number of huddles before they reach the nucleus of the target cells, such as enzymatic degradation in the bloodstream, extravascularization around the target tissue, ...
  • Molecular Imaging in the Aid of Drug Delivery Technology 
    Yong Woo Cho; ICK CHAN KWON; Kwangmeyung Kim; Kinam Park (The Polymer Society Of Korea, 2014-09)
    Molecular imaging aims to visualize biological processes in a living system at a molecular or cellularlevel while drug delivery systems (DDS) aim to deliver drugs to specific targets of tissues or organs at a controlledrate. ...
  • Multi-Core Vesicle Nanoparticles for Controlled Delivery of Protein Drug 
    Yuk， Soon Hong; Keun Sang Oh; 김승기; Jin Ho Lee; Sun Hang Cho; Kwangmeyung Kim; Hyesung Jeon; ICK CHAN KWON (The Polymer Society Of Korea, 2012-03)
    The Pluronic/poly(ethylene glycol) composite nanoparticles (NPs) composed of Pluronic F-68, liquid poly(ethylene glycol) (PEG; molecular weight, 400) and human growth hormone (hGH) were stabilized with the vesicle fusion. ...
  • Nano-enabled delivery systems across the blood–brain barrier 
    Seung Rim Hwang; Kwangmeyung Kim (The Pharmaceutical Society Of Korea, 2014-01)
    The development of drugs to treat disorders of the central nervous system (CNS) faces difficulties in achieving penetration of a drug through the blood–brain barrier (BBB) and allowing the drug to reach its intended target ...
  • Near-infrared Fluorescence Imaging Using a Protease-activatable Nanoprobe in Tumor Detection: Comparison with Narrow-band Imaging 
    Yoon， Soon Man; 김인화; 송미연; 도은주; 류주희; Kwangmeyung Kim; ICK CHAN KWON; 김미정; Dae Hyuk Moon; Dong-Hoon Yang; Kyung Jo Kim; Ye， Byong Duk; Byeon， Jeong-Sik; YANG， Suk-kyun; KIM， JIN-HO; MYUNG， SEUNG-JAE (Korean Association for the Study of Intestinal Disease, 2013-10)
    Background/Aims:Advances in endoscopic technology seek to improve the accuracy of neoplastic tumor detection. Recently developed endoscopy devices such as narrow-band imaging (NBI) nevertheless have limitations in morphologic ...
  • Near-Infrared Fluorescence Imaging Using a Protease-Specific Probe for the Detection of Colon Tumors 
    Soon Man Yoon; Seung-Jae Myung; Byong Duk Ye; In-Wha Kim; Nam Gon Lee; Yeon Mi Ryu; Park Kyeongsoon; Kwangmeyung Kim; Ick Chan Kwon; Young Soo Park; Dae Hyuk Moon; Do Hoon Kim; Mi Young Do; Jeong-Sik Byeon; Suk-Kyun Yang; Jin-Ho Kim (거트앤리버 소화기연관학회협의회, 2010-12)
    Background/Aims: Early tumor detection is crucial for the prevention of colon cancer. Near-infrared fluorescence (NIRF) imaging using a target-activatable probe may permit earlier disease detection. Matrix metalloproteinases ...
  • New Top Coating System of Chemically Anchored Phospholipid Monolayer on the Drug-encapsulated Polymer Film for Drug-Eluting Stent 
    Kwangmeyung Kim; 박상진; BYUN， YOUNGRO; 문현태 (The Polymer Society Of Korea, 2010-05)
    We report a novel method for preparing multi-layer polymer films as a matrix for local drug delivery that can be used as a drug-eluting stent. The base polymer matrix was an acrylated polymer film (poly(octadecyl ...
  • Self-Assembled Nanoparticles of Bile Acid-Modified Glycol Chitosans and Their Applications for Cancer Therapy 
    Kwangmeyung Kim; ICK CHAN KWON; InSan Kim; JEONG SEO YOUNG; Kuiwon Choi; Kim Yoo Shin; Jong-Ho Kim; Sungwon Kim; 정혜선; Jae Hyung Park; Rang-Won Park (The Polymer Society Of Korea, 2005-06)
    This review explores recent works involving the use of the self-assembled nanoparticles of bile acid-mod ified glycol chitosans (BGCs) as a new drug carrier for cancer therapy. BGC nanoparticles were produced by chem ically ...
  • 분자영상을 위한 다기능성 나노입자 
    강은아; Kwangmeyung Kim; ICK CHAN KWON (대한의사협회, 2009-02)
    Molecular imaging is a bioimaging that can detect biochemically and genetically relevant events in molecular level in cells and tissues via quantitative imaging signal. Molecular imaging provides potential advantages to ...
  • 요도용 카테타 도포용 양친성 폴리우레탄의 합성 및 분석 
    박재형; Kwangmeyung Kim; 정혜선; ICK CHAN KWON; 배유한; 정서영 (The Polymer Society Of Korea, 2006-05)
    말단에 하이드라이드 기가 치환된 폴리실록산과 알릴 메타아크릴레이트와의 하이드 로실릴레이션 반응을 통하여 폴리실록산 메타크릴레이트를 합성하였다. 또한 산촉매 하에서 옥타메틸사이클로테트라실록 산의 개환-부가반응을 통하여 분자량이 증가된 폴리실록산 메타 크릴레이트을 합성하였다. 합성된 폴리실 록산 메타크릴레이트는 1H- 및 29Si-NMR로 구조를 확인하였다. 폴리실록산 메타크릴레이트는 실리콘 오일과 ...
  • 진단 및 치료용 나노의약품 
    박재형; Kwangmeyung Kim; ICK CHAN KWON; Saravanakumar Gurusamy (The Korean Society Of Industrial And Engineering Chemistry, 2007-06)
    나노의약품(Nanomedicine)은 나노기술이 접목된 신기능성 의약품을 의미하며 빠르게 발전하고 있는 신생 분야이다. 아직 상용화된 나노의약품은 많지 않지만 최근 나노기술이 접목된 진단 및 치료제제가 속속 개발되면서 기존 의약품을 대체하는 추세에 있다. 나노의약품 연구는 지난 10여년 동안 미국과 유럽을 중심으로 활발히 진행되었으며, 그 결과로 2000년대에 접어서면서 나노의약품 관련 특허 ...

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