Browsing by Author "Wenfang Dou"

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Expression, Purification, and Bioactivity of (GLP-1A2G)2-HSA Analogs in Pichia pastoris GS115

Wenfang Dou; Junshang Feng; Xiaomei Zhang; Hongyu Xu; Jinsong Shi; Zhenghong Xu (The Korean Society For Biotechnology And Bioengineering, 2013-12)

We developed (GLP-1A2G)2-HSA (GGH) analogsthat are resistant to degradation and also show high serumglucose-reducing activity in vivo. Five analogs with Nterminalextensions were designed based on the proteinGGH. Next, we ...
Improvement of the Steroid Dihydroxylation Efficiency from Dehydroepiandrosterone Using a Substrate Pre-induction Biotransformation Process

Hui Li; Zhenzhen Fu; Heng Li; Wenfang Dou; Jinsong Shi; Zhenghong Xu (The Korean Society For Biotechnology And Bioengineering, 2013-06)

This study investigated the effects of hydroxylase cyptochrome P450 inducers on the efficiency of the biotransformation of dehydroepiandrosterone (DHEA) to 3β, 7α, 15α-trihydroxy-5-androsten-17-one (7α,15α-diOHDHEA)by ...

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