Background/Aims: Although several studies have shown that specialist care may be associated with better outcomes, methodological limitations have made it difficult to draw definitive conclusions. Therefore, we examined ...

Background/Aims: The optimal adjuvant chemotherapy and anti-human epidermal growth factor receptor 2 (HER2) therapy regimen following surgery for T1a/b HER2-positive breast cancer remains debatable. Methods: In this ...

Background/Aims: Hyperuricemia has been widely associated with cardiovascular health, but its relationship with incident valvular heart disease (VHD) remains uncertain. This study investigated the association between ...

Background/Aims: Residual inflammatory risk after acute myocardial infarction (AMI) remains an important determinant of long-term outcomes despite optimal lipid-lowering therapy. The prognostic significance of serial ...

Background/Aims: Digestive diseases are highly prevalent and contribute substantially to healthcare utilization and costs. However, national-level data on digestive diseases burden in Korea are limited. This study aimed ...

Sjögren syndrome (SS), traditionally regarded as a sicca-predominant condition, is now recognized as a systemic autoimmune disease characterized by type I interferon activation, B-cell hyperactivity, and periepithelial ...

Thrombotic thrombocytopenic purpura (TTP) is a rare but life-threatening thrombotic microangiopathy resulting from severe ADAMTS13 deficiency. Although effective treatments, such as therapeutic plasma exchange, immunosuppressive ...

Crohn’s disease (CD) is a chronic inflammatory disorder of the bowel characterized by alternating periods of remission and relapse. Although CD can affect any part of the gastrointestinal tract, small bowel involvement is ...